Insulin allergy is uncommon, particularly in patients with Type 2 diabetes. Management of the condition can be difficult, and here we report the case of a patient with Type 2 diabetes and insulin allergy successfully managed with a continuous subcutaneous insulin infusion (CSII).
Can you suddenly become allergic to insulin?
Generalized insulin allergy is rare. Symptoms occur immediately after the injection and include urticaria, angioedema, pruritus, bronchospasm, and, rarely, circulatory shock. As a rule, allergy may be treated with antihistamines.
What are the symptoms of being allergic to insulin?
Signs and Symptoms
- Irritation, swelling, or hives at injection site.
- Rash throughout the body.
- Low blood pressure.
- Shortness of breath.
- Anaphylaxis (throat and mouth swelling that restricts airways) – a life-threatening reaction.
What is the cause of insulin allergy?
Allergic reactions to insulin have been around since it was discovered in 1922. It was estimated that around half of people using these impure insulins had allergic reactions – thought to be caused by the insulin molecule as well as the preservatives or the agents used to slow down the action of insulin, such as zinc.
Which type of insulin is least allergic?
Insulin reactions occur rarely but are of tremendous clinical importance. The first was reported in 1922 as a callus reaction at the injection site of insufficiently purified bovine insulin. Porcine insulin was subsequently found to be less allergenic than bovine insulin.
How is insulin reaction treated?
What Is the Medical Treatment for Insulin Reaction? Increasing blood sugar levels is the treatment of an insulin reaction. Emergency personnel may start an intravenous line and inject an ampule of D50W, a highly concentrated glucose solution.
What is the side effects of insulin?
Insulin regular (human) side effects
- dizziness or lightheadedness.
- fast heart rate.
- tingling in your hands, feet, lips, or tongue.
- trouble concentrating or confusion.
- blurred vision.
What does an insulin rash look like?
People who have diabetes tend to get skin infections. If you have a skin infection, you’ll notice one or more of the following: Hot, swollen skin that is painful. An itchy rash and sometimes tiny blisters, dry scaly skin, or a white discharge that looks like cottage cheese.
Can insulin make me itchy?
Get emergency medical help if you have signs of insulin allergy: redness or swelling where an injection was given, itchy skin rash over the entire body, trouble breathing, fast heartbeats, feeling like you might pass out, or swelling in your tongue or throat.
Can insulin make you break out in hives?
Allergic reactions: People with diabetes may have an allergic reaction to oral diabetes medications or injectable insulin. You may develop a rash or hives and swelling (urticaria) at the injection site or elsewhere on your body. Contact your healthcare provider if you think you’re having an allergic reaction.
Why does my insulin injection site itchy?
Allergic reactions to insulin injections are usually due to the chemicals in the solution rather than the insulin itself. Now that insulin preparations are highly purified, allergic reactions are very rare. Individuals may develop a slightly raised, red, itchy lump at the site of an injection.
What can replace insulin?
In this Article
- Exenatide (Bydureon, Byetta)
- Liraglutide (Saxenda, Victoza)
- Pramlintide (Symlin)
- Dulaglutide (Trulicity)
- Semaglutide (Ozempic)