Why is Lantus changing to optisulin?

On 1 January 2020, Optisulin was listed with Lantus as ‘b’ flagged medicines and marked as equivalent for the purposes of substitution by pharmacists at the point of dispensing on the PBS General Schedule. Optisulin is the same formulation and delivery device as Lantus (cartridges for reusable injector pen devices).

What is the difference between Lantus and optisulin?

OPTISULIN® is the same formulation as Lantus®, so no dose adjustment is required. People living with diabetes should continue using insulin to manage their diabetes as directed by their healthcare professional. People living with diabetes who are currently using LANTUS® will need to change to a new brand of insulin.

What happened to Lantus?

The latest one going is Lantus, which will be discontinued from the Pharmaceutical Benefits Scheme (PBS) as of June 30, 2020. Lantus is the registered trade name for a long-acting insulin called Insulin Glargine, produced by Sanofi.

What is the new Lantus?

By Donna Itzen, Pharmacist Diabetes QLD. Sanofi has released a second brand formulation of insulin glargine 100 units/ml. The new preparation is called OPTISULIN® and is already listed on the Pharmaceutical Benefits Scheme (PBS) as of 1st January, 2020.

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Is Lantus going generic?

Viatris’s Semglee was first approved last year, but its new interchangeable label means that it can be substituted for the reference product, Sanofi’s long-acting Lantus, at US pharmacies, like a generic.

Biosimilar versions of Sanofi’s Lantus (insulin glargine)
Company Product Status

How does optisulin Solostar work?

Optisulin is used to reduce high blood sugar (glucose) levels in people with diabetes mellitus. Optisulin is a modified insulin that is very similar to human insulin. It is a substitute for the insulin produced by the pancreas. Optisulin is a long-acting insulin.

Is optisulin a biosimilar?

Optisulin® is a second brand of insulin glargine made by the same manufacturer as Lantus®. Semglee® is a biosimilar insulin glargine made by a different manufacturer. Lantus®, Optisulin® and Semglee® products all contain 100 units/mL of insulin glargine.

How do you use optisulin insulin?

Use a new pen. Optisulin should be injected under the skin, being careful not to inject it into a muscle or vein. Choose a site for injection. Inject Optisulin into the abdomen, thighs or upper arms.

When do you split long-acting insulin?

When basal insulin is injected twice daily, it is reasonable to split the doses evenly and take them approximately 12 hours apart. Taking more in the evening and less in the morning does not usually produce a desired “peak” at any particular time.

How do I use optisulin?

Use a new pen. Optisulin should be injected under the skin, being careful not to inject it into a muscle or vein. Choose a site for injection. Inject Optisulin into the abdomen, thighs or upper arms.

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Is all Lantus the same?

Others include Levemir and Toujeo. Long-acting insulins, often called basal insulins, are taken once a day to control blood sugar throughout the day. Lantus and Basaglar are rather interesting in that they are essentially the same drug with the same active ingredient: insulin glargine. But, they’re not interchangeable.

What insulin can replace Lantus?

Back in 2016, manufacturers Eli Lilly and Boehringer Ingelheim launched a new long-acting insulin, Basaglar, and marketed it as the cheaper alternative to blockbuster insulin Lantus.

Is there a better insulin than Lantus?

The biggest difference is that Toujeo is highly concentrated, making injection volume much smaller than Lantus. In terms of side effects, one important factor to consider is that Toujeo may offer less risk for hypoglycemia, or low blood glucose, than Lantus, because it helps keep blood sugar levels more consistent.

Is Basalog and Lantus same?

Basalog® is a new insulin glargine developed by Biocon Limited expressed in a non-pathogenic yeast Pichia pastoris, with the same amino acid sequence as Lantus®.

Is 80 units of Lantus too much?

It is possible that the “maximum” of 50 units is derived from the technical limitations of the 1/2 mL syringe. The Lantus SoloStar disposable pen has a maximum “dial-able” dose of 80 units. Aside from this technical maximum, there is no mention of a maximum dose in the package insert.

Can I substitute Semglee for Lantus?

Semglee is an interchangeable biosimilar with Lantus, which means that there aren’t clinically meaningful differences (e.g., safety and effectiveness) between the two insulins and they can be substituted for each other.

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