Which of the following is a life threatening acute complication of diabetes mellitus?
Diabetic ketoacidosis (DKA), hyperglycemic hyperosmolar state (HHS), lactic acidosis (LA), and hypoglycemia are acute and potentially life-threatening complications of diabetes.
Which of the following contributes to the development of ketoacidosis in a diabetic patient?
In general diabetic ketoacidosis occurs because there is not enough insulin to move sugar (glucose) into the cell where it can be used for energy. Besides lack of insulin, certain body stressors combined with diabetes, such as infection or illness, can trigger diabetic ketoacidosis.
Which of the following is associated with the development of ketoacidosis?
Diabetic ketoacidosis is a serious complication of diabetes that occurs when your body produces high levels of blood acids called ketones. The condition develops when your body can’t produce enough insulin.
What is the most significant basic defect in the development of DKA?
The major cause of water deficit in DKA and HHS is glucose-mediated osmotic diuresis, which leads to loss of water in excess of electrolytes (97).
What are 3 acute complications of diabetes?
Acute complications include diabetic ketoacidosis, hyperosmolar hyperglycemic nonketotic coma, and hypoglycemia.
What are the life-threatening complications of diabetes?
Diabetes can lead to both life-threatening and life-altering problems. They include blindness, heart and blood vessel disease, stroke, kidney failure, amputations and nerve damage. Many of these problems can be avoided by adopting healthy lifestyle habits and taking steps to monitor and control your diabetes.
Is DKA life-threatening?
Elevated ketones are a sign of DKA, which is a medical emergency and needs to be treated right away. Diabetic ketoacidosis (DKA) is a serious complication of diabetes that can be life-threatening. DKA is most common among people with type 1 diabetes. People with type 2 diabetes can also develop DKA.
What causes canine ketoacidosis?
Causes. Although the ketoacidosis is ultimately brought on by the dog’s insulin dependency due to diabetes mellitus, underlying factors include stress, surgery, and infections of the skin, respiratory, and urinary tract systems.
What causes vomiting in DKA?
As ketones accumulate in the blood, more ketones will be passed in the urine, taking sodium and potassium salts out with them. Over time, levels of sodium and potassium salts in the body become depleted, which can cause nausea and vomiting. The result is a vicious cycle. Dehydration is another complication of DKA.
Which condition is also known as diabetic ketoacidosis?
Diabetic ketoacidosis (DKA) is a serious complication of type 1 diabetes and, much less commonly, of type 2 diabetes. DKA happens when your blood sugar is very high and acidic substances called ketones build up to dangerous levels in your body.
Does DKA cause hyperkalemia or hypokalemia?
DKA is a well-known cause of hypokalemia caused by osmotic diuresis leading to a total body potassium deficiency of 3 to 6 mEq/kg. At presentation, potassium levels are typically “normal” due to the extracellular shift of potassium (K+) from insulin deficiency and acidosis.
What organs are affected by ketoacidosis?
Fluid loss from DKA can lead to kidney and organ damage, brain swelling that can eventually cause a coma, and fluid buildup in your lungs.
Which complication of diabetes can cause hypoglycemia unawareness?
If you are like approximately 40% of people with Type 1 diabetes, you probably have some degree of hypoglycemia unawareness. This is a complication of T1D during which patients experience severe low blood sugars but do not feel them.
What acid base disturbances commonly occur in DKA?
Acidosis in DKA is due to the overproduction of β-hydroxybutyric acid and acetoacetic acid. At physiological pH, these 2 ketoacids dissociate completely, and the excess hydrogen ions bind the bicarbonate, resulting in decreased serum bicarbonate levels.
When managing diabetic ketoacidosis which intervention is appropriate?
Fluid replacement is one of the most important initial therapeutic interventions in the management of DKA. Patients are usually dehydrated and correcting this deficit will result in significant metabolic improvement (Kitabchi et al, 2004).