Which is better Clomid or metformin?

The authors came to the following conclusion: Clomiphene is superior to metformin in achieving live birth in infertile women with the polycystic ovary syndrome, although multiple birth is a complication.

What are the chances of getting pregnant with metformin and Clomid?

The metformin and clomiphene combination resulted in a significantly higher rate of ovulation (P = 0.0016). The pregnancy rate was 8% with CC and 24% with metformin and CC.

Is it okay to take Clomid and metformin together?

Using clomiphene and metformin together can be beneficial for the women with polycystic ovarian syndrome. If they can ovulate and get pregnant with this medication combination, they can avoid the more expensive and invasive treatments such as using injectable FSH medications or in vitro fertilization for PCOS.

Does metformin make you ovulate more?

Metformin probably improves ovulation in women with PCOS by reducing gluconeogenesis, improving insulin sensitivity, and reducing ovarian androgen production (8, 9).

Why is Clomid not recommended?

Though Clomid is generally well tolerated by most people, in some cases it can lead to changes in a woman’s cervical mucus and have endometrial effects that can negatively impact success rates. There is no evidence that shows increasing the dosage of Clomid will result in an increase in pregnancy rates.

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Did anyone get pregnant on metformin?

At the end of the CC cycles 4.2% of patients got pregnant and 65.2% of the remaining group got pregnant with metformin plus CC cycles (p=0.0001). We have not observed any serious side effects of metformin.

How much metformin should I take to get pregnant?

However, the optimal regimen for metformin has not been determined; doses of between 500 mg/day and 3000 mg/day have been used, with the most common regimens being 500 mg three times daily or 850 mg twice daily.

Is metformin a fertility drug?

While metformin can be used for the treatment of infertility, it is not a fertility drug. When taken to treat infertility, it is considered an off-label use (which means that pregnancy achievement is not the original intended purpose of the drug).

Can metformin cause twin pregnancy?

The additive effects of adjunctive treatments such as weight reduction, ovarian drilling, and clomiphene and metformin therapy may result in an increased incidence of higher-order multiple pregnancy and women need to be counseled about this risk.

How long do you take metformin for PCOS?

Metformin improves menstrual cycle regularity and lowers body mass index (BMI), testosterone, and luteinizing hormone (LH) within 6 months of treatment in women with polycystic ovary syndrome (PCOS) who are normal weight or overweight, new results show.

Does Clomid improve egg quality?

To address your last question, Clomid will not affect the egg quality.

How many rounds of Clomid does it take to get pregnant?

If three to six cycles of Clomid don’t lead to pregnancy, new treatment options may be considered. Six cycles of Clomid is considered to be the top limit, though some doctors suggest moving on if pregnancy doesn’t occur by the third treatment cycle.

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Can I take folic acid and Clomid at the same time?

Interactions between your drugs

No interactions were found between clomiphene and folic acid. This does not necessarily mean no interactions exist. Always consult your healthcare provider.