What is iatrogenic hyperglycemia?

A severe and potentially fatal condition is iatrogenic severe hyperglycemia (ISH) following administration of glucose-containing i.v. solution. It occurs due to human errors regarding prescription, preparation and administration of glucose-containing medication or parenteral nutrition.

What is iatrogenic diabetes?

Despite guidelines on diabetes care, maintaining glycemic control in diabetic patients is challenging and medical intervention is not without risk. 15,16 Medical providers, treatments, and procedures can all cause complications. These complications are known as iatrogenic.

What is iatrogenic hypoglycemia?

Iatrogenic hypoglycemia was defined as hypoglycemia (glucose ≤50 mg/dL) that occurred in the ED caused by 1) ED insulin administration, or 2) unrecognized or inadequately treated malnutrition.

What is drug induced hyperglycemia?

Medications that enhance glycogenolysis or gluconeogenesis may result in hyperglycemia. In addition, excessive glucose intake, particularly through a parenteral route, may overwhelm the pancreatic capacity of insulin production and cause hyperglycemia.

What are the 3 signs of hyperglycemia?

What are the symptoms of hyperglycemia?

  • High blood sugar.
  • Increased thirst and/or hunger.
  • Blurred vision.
  • Frequent urination (peeing).
  • Headache.

What is hypoglycemia associated autonomic failure?

The concept of hypoglycemia-associated autonomic failure (HAAF) in diabetes posits that recent antecedent iatrogenic hypoglycemia causes both defective glucose counterregulation (by reducing the epinephrine response to falling glucose levels in the setting of an absent glucagon response) and hypoglycemia unawareness ( …

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Does Glycogenolysis correct hypoglycemia?

When blood glucose levels drop too low, the release of epinephrine and another hormone, glucagon, stimulates glycogenolysis to restore blood glucose levels to normal. People with type 1 diabetes may eventually lose the ability to secrete glucagon and epinephrine, setting the stage for severe hypoglycemia.

Which medication could cause a risk for hyperglycemia?

Common drug categories and drugs associated with contributing to hyperglycemia are discussed below.

  • Antibiotics (Fluoroquinolones) …
  • β-blockers. …
  • Thiazide and Thiazide-Like Diuretics. …
  • Second-Generation Antipsychotics (SGAs) …
  • Corticosteroids. …
  • Calcineurin Inhibitors (CNIs) …
  • Protease Inhibitors. …
  • Clinical Management.

What causes hyperglycemia?

Many factors can contribute to hyperglycemia, including: Not using enough insulin or oral diabetes medication. Not injecting insulin properly or using expired insulin. Not following your diabetes eating plan.

Does prednisolone cause hyperglycemia?

Prednisone and other steroids can cause a spike in blood sugar levels by making the liver resistant to insulin. The pancreas produces insulin to control blood sugar levels.

Can drinking water lower blood sugar?

Drinking water regularly may rehydrate the blood, lower blood sugar levels, and reduce diabetes risk ( 20 , 21 ).

How do you manage a patient with hyperglycemia?


  1. Get physical. Regular exercise is often an effective way to control your blood sugar. …
  2. Take your medication as directed. …
  3. Follow your diabetes eating plan. …
  4. Check your blood sugar. …
  5. Adjust your insulin doses to control hyperglycemia.

What’s the difference between hyperglycemia and diabetes?

Hyperglycemia, or high blood glucose, is a symptom that characterizes diabetes. Insufficient insulin production, resistance to the actions of insulin, or both can cause diabetes to develop. When a person eats carbohydrates, the body breaks them down into simple sugars that enter the bloodstream.

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