Quetiapine is known to be able to induce mild hypoglycemia in patients without diabetes. We report on our experience treating an older individual without diabetes who developed severe hypoglycemia as a result of administration of quetiapine.
Does Seroquel affect blood sugar?
Taking Seroquel (quetiapine) can cause episodes of hyperglycemia (high blood sugar), even if you do not have diabetes. If high blood sugar isn’t treated promptly, it can lead to a dangerous condition called ketoacidosis.
What medication is most likely to cause hypoglycemia?
Medicines that can cause drug-induced low blood sugar include:
- Beta-blockers (such as atenolol, or propranolol overdose)
- Cibenzoline and quinidine (heart arrhythmia drugs)
- Glinides (such as nateglinide and repaglinide)
- Indomethacin (a pain reliever)
- Metformin when used with sulfonylureas.
What psych meds cause hypoglycemia?
Hypersecretion of insulin by antipsychotics is thought to be a key mechanism of antipsychotic-induced severe hypoglycemia.
Can antipsychotics cause hypoglycemia?
Atypical antipsychotics cause hypoglycemia as a rare metabolic adverse effect in patients without diabetes.
Can quetiapine cause hyperglycemia?
Quetiapine treatment has been reported to be associated with the development of hyperglycemia17 and new-onset diabetes mellitus,22 with most cases of hyperglycemia occurring within three months. However, quetiapine therapy is not associated with a consistent increase in the risk of developing diabetes.
Can antipsychotics affect blood sugar?
Antipsychotics likely increase the risk of diabetes through weight gain and directly by adversely affecting insulin sensitivity and secretion.
Why do I suddenly have hypoglycemia?
In people without diabetes, hypoglycemia can result from the body producing too much insulin after a meal, causing blood sugar levels to drop. This is called reactive hypoglycemia. Reactive hypoglycemia can be an early sign of diabetes.
What can worsen hypoglycemia?
But too much insulin or other diabetes medications may cause your blood sugar level to drop too low, causing hypoglycemia. Hypoglycemia can also occur if you eat less than usual after taking diabetes medication, or if you exercise more than you normally do.
Which medication has the lowest risk for hypoglycemia?
Of the newer generation sulfonylureas, gliclazide is associated with the lowest risk of hypoglycemia when added to metformin, according to a systematic review and meta-analysis published online Aug. 3 in the British Journal of Clinical Pharmacology.
What antidepressants cause low blood sugar?
Antidepressants, including SSRIs and tricyclic antidepressants, have been found to interfere with blood glucose metabolism, increasing the risk of hypoglycemic episodes. Several reports have implicated antidepressants, especially SSRIs, in the development of clinically relevant hypoglycemia in diabetic patients.
What are the most common causes of a patient experiencing hypoglycemia?
Common causes of diabetic hypoglycemia include:
- Taking too much insulin or diabetes medication.
- Not eating enough.
- Postponing or skipping a meal or snack.
- Increasing exercise or physical activity without eating more or adjusting your medications.
- Drinking alcohol.
Which antipsychotics cause high blood sugar?
Clozapine and olanzapine are considered the worst offenders for contributing to hyperglycemia, dyslipidemia, and weight gain. Intermediate effects are seen with risperidone and quetiapine, while ziprasidone and aripiprazole are considered to convey the smallest relative risk.
What drugs mask the symptoms of hypoglycemia?
Furthermore, β-blockers have the potential for masking symptoms of hypoglycemia. The catecholamine-mediated neurogenic hypoglycemic symptoms masked by this class of medications include tremor and palpitations. Hunger, tremor, irritability, and confusion may be concealed as well.
Which antipsychotic does not affect blood sugar?
Ziprasidone and lurasidone were associated with minimal glucose changes compared to the other antipsychotics.