And 77% of metformin users with vitamin B12 deficiency also had peripheral neuropathy, a common form of nerve damage associated with type 2 diabetes. Peripheral neuropathy is a type of nerve damage most often characterized by pain, tingling, and numbness in the hands and feet.
Is neuropathy a side effect of metformin?
Metformin-treated diabetics (MTD) showed a decrease in cobalamin, a rise in homocysteine, and methylmalonic acid, leading to accentuated diabetic peripheral neuropathy (DPN).
What are the most common side effects of metformin?
The most common side effects of metformin include:
- stomach pain.
- nausea or vomiting.
- weight loss.
Does diabetic neuropathy go away?
Diabetic neuropathy has no known cure. The goals of treatment are to: Slow progression of the disease. Relieve pain.
Can metformin cause paresthesia?
Metformin use is associated with vitamin B12 deficiency and can result in neuropathy, ranging from paresthesia and decreased peripheral sensation to changes in mental status .
Can stopping metformin cause neuropathy?
Risks of stopping metformin
If left untreated, high blood glucose levels can lead to complications, such as: impaired vision, or diabetic retinopathy. kidney problems, or diabetic nephropathy. nerve damage, or diabetic neuropathy.
What are the long term effects of taking metformin?
The medication can cause more serious side effects, though these are rare. The most serious of these is lactic acidosis, a condition caused by buildup of lactic acid in the blood. This can occur if too much metformin accumulates in the blood due to chronic or acute (e.g. dehydration) kidney problems.
What should I avoid while taking metformin?
Avoid consuming large amounts of alcohol while on metformin. Drinking alcohol while taking metformin increases your risk of developing low blood sugar or even lactic acidosis. According to the University of Michigan, you should avoid eating high-fiber foods after taking metformin.
What happens when you take metformin and eat sugar?
There are no foods that are off-limits with metformin. However, you should be eating a healthy diet to help control your diabetes. When you eat sugar and metformin, your body will have to work harder to lower your blood sugars.
How much metformin can you take in a day?
The maximum daily dose is 2,000mg a day (for example, 4 x 500mg tablets). Metformin tablets come in different strengths. Your doctor will tell you how many tablets to take a day.
How do I stop diabetic tingling?
Some physical therapy treatments, such as swimming, can help treat diabetic neuropathy. Low-impact exercises are the most effective, as high-impact exercises can quickly cause nerves to go numb.
What can I do for neuropathy in my hands?
- Pain relievers. Over-the-counter pain medications, such as nonsteroidal anti-inflammatory drugs, can relieve mild symptoms. …
- Anti-seizure medications. …
- Topical treatments. …
How do I stop my hands and feet from tingling?
Here are 5 steps to try:
- Take the pressure off. Taking pressure off of the affected nerve allows it to regain normal function. …
- Move around. Moving around could improve circulation and relieve the uncomfortable sensations you’re experiencing. …
- Clench and unclench your fists. …
- Wiggle your toes. …
- Rock your head side to side.
How much vitamin B12 should I take with metformin?
Thus, annual injections of vit B12 (in a dose of 1 mg) given to every patient on long-term metformin therapy will be a more practical and cost-effective method. This method will ensure replenishment of vit B12 stores for at least 1 year. It will also obviate the need for annual screening of vit B12 levels.
What is an alternative to metformin?
Another type of drug, called salicylate, works in a similar way to metformin and scientists think it could be a good alternative for people with type 2 diabetes who can’t take metformin. Salicylate is already used to treat other health problems, like pain and inflammation.
How can I reduce the side effects of metformin?
To reduce all gastrointestinal side effects, take your Metformin with meals. If you need to take it at a time when you don’t usually eat, then fit a snack in that has some protein in it. Chewing gum can help alleviate various gastrointestinal side effects such as nausea and stomach pain. Keep some gum on hand.