Neuroglycopenic symptoms include weakness, tiredness, or dizziness; inappropriate behavior (sometimes mistaken for inebriation), difficulty with concentration; confusion; blurred vision; and, in extreme cases, coma and death.
What are the neurogenic and neuroglycopenic symptoms of hypoglycemia?
Can low blood sugar cause neurological problems?
These symptoms prompt individuals to ingest food to increase blood sugar levels. If these defenses are unable to restore blood sugar levels, inadequate glucose supply to the brain leads to neuroglycopenic symptoms such as confusion, difficulty speaking, ataxia, paresthesias, headaches, seizures, and coma.
How does hypoglycemia affect brain function?
Hypoglycemia commonly causes brain fuel deprivation, resulting in functional brain failure, which can be corrected by raising plasma glucose concentrations. Rarely, profound hypoglycemia causes brain death that is not the result of fuel deprivation per se.
What part of the brain is affected by hypoglycemia?
Hypoglycemia often differs from ischemia in its neuropathologic distribution, in that necrosis of the dentate gyrus of the hippocampus can occur and a predilection for the superficial layers of the cortex is sometimes seen. Cerebellum and brainstem are universally spared in hypoglycaemic brain damage.
What is hypoglycemia unawareness?
Hypoglycemia unawareness (HU) is defined as the onset of neuroglycopenia before the appearance of autonomic warning symptoms or as the failure to sense a significant fall in blood glucose below normal levels.
What is hypoglycemic encephalopathy?
Hypoglycemic encephalopathy is a metabolic encephalopathy due to extremely low blood glucose. Such patients often suffer from the disease suddenly, which is initially characterized by multiple symptoms such as lags in response, confusion, mental and behavior disorders, and adverse physical activity.
What are neurological complications of diabetes?
Diabetic neuropathy most often damages nerves in your legs and feet. Depending on the affected nerves, diabetic neuropathy symptoms can range from pain and numbness in your legs and feet to problems with your digestive system, urinary tract, blood vessels and heart. Some people have mild symptoms.
Why would repetitive episodes of hypoglycemia be a neurological issue?
A major concern of diabetic patients is that repeated episodes of hypoglycemia may result in neuronal loss because of impaired fuel supply.
How low does your sugar have to be to go into a coma?
A diabetic coma could happen when your blood sugar gets too high — 600 milligrams per deciliter (mg/dL) or more — causing you to become very dehydrated. It usually affects people with type 2 diabetes that isn’t well-controlled.
Can hypoglycemia cause long term effects?
Low blood sugar levels have few direct links to critical long-term effects, but they can increase a person’s vulnerability to other conditions, such as heart disease.
Which of the following describes adrenergic symptoms of hypoglycemia?
Adrenergic features, when present, precede neurobehavioral features, thus functioning as an early warning system. Inpatient team members must be alert to early adrenergic hypoglycemia signs and symptoms, including anxiety, irritability, dizziness, diaphoresis, pallor, tachycardia, headache, shakiness, and hunger.
What symptoms of hypoglycemia do beta blockers mask?
Furthermore, β-blockers have the potential for masking symptoms of hypoglycemia. The catecholamine-mediated neurogenic hypoglycemic symptoms masked by this class of medications include tremor and palpitations. Hunger, tremor, irritability, and confusion may be concealed as well.
Is paresthesia a symptom of hypoglycemia?
Peripheral neural injury has been reported in patients with hypoglycemia due to insulinomas (5). These patients displayed paresthesias and/or muscle wasting and weakness.